What are Glucosamine and Chondroitin Sulfate?
Glucosamine and chondroitin sulfate are substances found naturally in the body. Glucosamine is a form of amino sugar that is believed to play a role in cartilage formation and repair. Chondroitin sulfate is part of a large protein molecule (proteoglycan) that gives cartilage elasticity.
Both glucosamine and chondroitin sulfate are sold as dietary or nutritional supplements. They are extracted from animal tissue: glucosamine from crab, lobster or shrimp shells; and chondroitin sulfate from animal cartilage, such as tracheas or shark cartilage.
What do they do?
Past studies show that some people with mild to moderate osteoarthritis (OA) taking either glucosamine or chondroitin sulfate reported pain relief at a level similar to that of nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin and ibuprofen. Some research indicates that the supplements might also slow cartilage damage in people with OA. Definitive results about the effects of these supplements are expected from an in-depth clinical study currently being conducted by the National Institutes of Health.
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What is Chondroitin sulfate
Many forms of joint pain are directly related to a deficiency of healthy cartilage in the joints. The cartilage that lubricates and cushions the joints of the body experiences wear and tear on a daily basis. In healthy joints, wear and tear is repaired via a biological balancing process. In order to keep joints healthy, damaged cartilage is constantly being removed through the enzymatic deconstruction and replaced via new cartilage synthesis. This balance is crucial to good joint health.
As many people and animals age, their bodies progressively loose the ability to synthesize the glycosaminoglycans necessary to synthesize the new cartilage tissues needed to repair injuries and everyday wear and tear.
Durring times of stress (such as injury) or disease (i.e. certain forms of arthritis) the deconstructive enzymes in the joints may attack healthy cartilage or compete against new cartilage synthesis.
Where does it come from?
While Chondroitin Sulfate is found in the cartilaginous tissues of many invertebrates, the Chondroitin Sulfate utilized in health food supplements is usually derived from Cattle, Pigs, or Sharks.
What source is best?
When good quality materials are compared, it is believed that the source of the material has little to do with its effectiveness. Companies usually choose a material based upon varying economical, social and ethical standards.
For example, in markets where customers are especially sensitive to the issue of BSE - Mad Cow's Disease (such as certain European markets), a company may choose to utilize a shark material rather than one from a bovine source (cattle). On the other hand, Bovine material may be more appropriate for a customer that is interested in a material to satisfy a market that understands BSE and the precautions taken by companies such as IRMA Corporation to ensure product safety.
IRMA Corporation provides cartilage derived from several animal sources. Our representatives are prepared to answer questions regarding any other concerns and sensitivities that may arise.
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